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Dual Mechanism of a Natural CaMKII Inhibitor

Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a major mediator of cellular Ca(2+) signaling. Several inhibitors are commonly used to study CaMKII function, but these inhibitors all lack specificity. CaM-KIIN is a natural, specific CaMKII inhibitor protein. CN21 (derived from CaM-KI...

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Main Authors: Vest, Rebekah S., Davies, Kurtis D., O'Leary, Heather, Port, J. David, Bayer, K. Ulrich
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096578/
https://ncbi.nlm.nih.gov/pubmed/17942605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0185
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