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Targeting mutant p53 shows promise for sunscreens and skin cancer

Chronic exposure to UV light is a risk factor for skin cancer in which signature mutations in the p53 tumor suppressor gene occur due to DNA damage and contribute to cancer development. In this issue of the JCI, Tang et al. report on their study of a nonimmunodeficient mouse model of UVB-induced ski...

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Hlavní autor: El-Deiry, Wafik S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096462/
https://ncbi.nlm.nih.gov/pubmed/18060027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34251
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