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Therapeutic targeting of the p53 pathway in cancer stem cells

INTRODUCTION: Cancer stem cells are a high profile drug target for cancer therapeutics due to their indispensable role in cancer progression, maintenance, and therapeutic resistance. Restoring wild-type p53 function is an attractive new therapeutic approach for the treatment of cancer due to the wel...

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Detalhes bibliográficos
Main Authors: Prabhu, Varun V., Allen, Joshua E., Hong, Bo, Zhang, Shengliang, Cheng, Hairong, El-Deiry, Wafik S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650610/
https://ncbi.nlm.nih.gov/pubmed/22998602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2012.726985
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