IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

High serum levels of IL-6 correlate with poor outcome in breast cancer patients. However, no data are available on the relationship between IL-6 and mammary stem/progenitor cells, which may fuel the genesis of breast cancer in vivo. Herein, we address this issue in the MCF-7 breast cancer cell line...

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Main Authors: Sansone, Pasquale, Storci, Gianluca, Tavolari, Simona, Guarnieri, Tiziana, Giovannini, Catia, Taffurelli, Mario, Ceccarelli, Claudio, Santini, Donatella, Paterini, Paola, Marcu, Kenneth B., Chieco, Pasquale, Bonafè, Massimiliano
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096439/
https://ncbi.nlm.nih.gov/pubmed/18060036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32533
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