Cyclooxygenase-2/carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells

Inflammation promotes colorectal carcinogenesis. Tumour growth often generates a hypoxic environment in the inner tumour mass. We here report that, in colon cancer cells, the expression of the pro-inflammatory enzyme cyclooxygenase-2 (COX-2) associates with that of the hypoxia response gene carbonic...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Sansone, Pasquale, Piazzi, Giulia, Paterini, Paola, Strillacci, Antonio, Ceccarelli, Claudio, Minni, Francesco, Biasco, Guido, Chieco, Pasquale, Bonafè, Massimiliano
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
Assuntos:
Molecular Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516535/
https://ncbi.nlm.nih.gov/pubmed/19017360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00580.x
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