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Structural Basis of J Cochaperone Binding and Regulation of Hsp70
The many protein processing reactions of the ATP-hydrolyzing Hsp70s are regulated by J cochaperones, which contain J domains that stimulate Hsp70 ATPase activity and accessory domains that present protein substrates to Hsp70s. We report the structure of a J domain complexed with a J responsive porti...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096417/ https://ncbi.nlm.nih.gov/pubmed/17996706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.08.022 |
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