The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA

Saccharomyces cerevisiae DNA polymerase δ (Pol δ) and DNA polymerase ε (Pol ε) are replicative DNA polymerases at the replication fork. Both enzymes are stimulated by PCNA, although to different levels. To understand why and to explore the interaction with PCNA, we compared Pol δ and Pol ε in physic...

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Bibliographische Detailangaben
Hauptverfasser: Chilkova, Olga, Stenlund, Peter, Isoz, Isabelle, Stith, Carrie M., Grabowski, Pawel, Lundström, Else-Britt, Burgers, Peter M., Johansson, Erik
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2007
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095795/
https://ncbi.nlm.nih.gov/pubmed/17905813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm741
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