The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA

Saccharomyces cerevisiae DNA polymerase δ (Pol δ) and DNA polymerase ε (Pol ε) are replicative DNA polymerases at the replication fork. Both enzymes are stimulated by PCNA, although to different levels. To understand why and to explore the interaction with PCNA, we compared Pol δ and Pol ε in physic...

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Detalhes bibliográficos
Main Authors: Chilkova, Olga, Stenlund, Peter, Isoz, Isabelle, Stith, Carrie M., Grabowski, Pawel, Lundström, Else-Britt, Burgers, Peter M., Johansson, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095795/
https://ncbi.nlm.nih.gov/pubmed/17905813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm741
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