Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes

Interaction of the T cell receptor (TCR) with peptide/major histocompatibility complexes (MHC) in the thymus is of critical importance for developing thymocytes. In a previous study, we described an antagonist peptide that inhibited negative selection of transgenic thymocytes induced by an agonist p...

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Главные авторы: Smyth, Lesley A., Williams, Owen, Huby, Russell D. J., Norton, Trisha, Acuto, Oreste, Ley, Steven C., Kioussis, Dimitris
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC20952/
https://ncbi.nlm.nih.gov/pubmed/9653163
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