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Up-regulation of proteinase-activated receptor 1 and increased contractile responses to thrombin after subarachnoid haemorrhage

BACKGROUND AND PURPOSE: The mechanism for the development of post-haemorrhagic cerebral vasospasm after subarachnoid haemorrhage (SAH) still remains unknown. EXPERIMENTAL APPROACH: We investigated the role of thrombin and its receptor PAR(1) in the development of hyper-contractility of the basilar a...

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Autors principals: Maeda, Y, Hirano, K, Kai, Y, Hirano, M, Suzuki, S O, Sasaki, T, Kanaide, H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095114/
https://ncbi.nlm.nih.gov/pubmed/17767169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707435
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