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Combined argatroban and anti-oxidative agents prevents increased vascular contractility to thrombin and other ligands after subarachnoid haemorrhage

BACKGROUND AND PURPOSE: Increased vascular contractility plays a fundamental role in cerebral vasospasm in subarachnoid haemorrhage (SAH). We investigated the role of thrombin and its receptor, proteinase-activated receptor 1 (PAR1), and other G protein-coupled receptors in the increased contractili...

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Bibliografiske detaljer
Main Authors: Kameda, Katsuharu, Kikkawa, Yuichiro, Hirano, Mayumi, Matsuo, Satoshi, Sasaki, Tomio, Hirano, Katsuya
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252971/
https://ncbi.nlm.nih.gov/pubmed/21564089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01485.x
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