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HD mice: A novel mouse mutant with a specific defect in the generation of CD4(+) T cells

We have identified a spontaneous mutation in mice, which we term HD for “helper T cell deficient.” This mouse is distinguished by the virtual absence of peripheral T cells of the CD4(+)8(−) major histocompatibility complex (MHC) class II-restricted T helper subset due to a specific block in thymic d...

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Bibliographische Detailangaben
Hauptverfasser: Dave, Vibhuti P., Allman, David, Keefe, Robert, Hardy, Richard R., Kappes, Dietmar J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20951/
https://ncbi.nlm.nih.gov/pubmed/9653162
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