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HD mice: A novel mouse mutant with a specific defect in the generation of CD4(+) T cells
We have identified a spontaneous mutation in mice, which we term HD for “helper T cell deficient.” This mouse is distinguished by the virtual absence of peripheral T cells of the CD4(+)8(−) major histocompatibility complex (MHC) class II-restricted T helper subset due to a specific block in thymic d...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The National Academy of Sciences
1998
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20951/ https://ncbi.nlm.nih.gov/pubmed/9653162 |
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