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Developmental pathway of CD4(+)CD8(−) medullary thymocytes during mouse ontogeny and its defect in Aire(−/−) mice
The newly generated single-positive (SP) thymocytes undergo further maturation in the thymic medulla before their emigration to the periphery. The present study was undertaken to validate a developmental program we proposed for CD4SP medullary thymocytes and to explore the mechanisms regulating this...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084316/ https://ncbi.nlm.nih.gov/pubmed/17984055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708884104 |
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