Single amino acid substitution in prokaryote polypeptide release factor 2 permits it to terminate translation at all three stop codons

Prokaryotic translational release factors, RF1 and RF2, catalyze polypeptide release at UAG/UAA and UGA/UAA stop codons, respectively. In this study, we isolated a bacterial RF2 mutant (RF2*) containing an E167K substitution that restored the growth of a temperature-sensitive RF1 strain of Escherich...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ito, Koichi, Uno, Makiko, Nakamura, Yoshikazu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8165
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