Single amino acid substitution in prokaryote polypeptide release factor 2 permits it to terminate translation at all three stop codons
Prokaryotic translational release factors, RF1 and RF2, catalyze polypeptide release at UAG/UAA and UGA/UAA stop codons, respectively. In this study, we isolated a bacterial RF2 mutant (RF2*) containing an E167K substitution that restored the growth of a temperature-sensitive RF1 strain of Escherich...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8165 |
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