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Single amino acid substitution in prokaryote polypeptide release factor 2 permits it to terminate translation at all three stop codons

Prokaryotic translational release factors, RF1 and RF2, catalyze polypeptide release at UAG/UAA and UGA/UAA stop codons, respectively. In this study, we isolated a bacterial RF2 mutant (RF2*) containing an E167K substitution that restored the growth of a temperature-sensitive RF1 strain of Escherich...

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Hlavní autoři: Ito, Koichi, Uno, Makiko, Nakamura, Yoshikazu
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC20947/
https://ncbi.nlm.nih.gov/pubmed/9653158
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