Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis

Two distinct IL-18 neutralizing strategies, i.e. a rabbit polyclonal anti-mouse IL-18 IgG and a recombinant human IL-18 binding protein (rhIL-18BP), were used to treat collagen-induced–arthritic DBA/1 mice after clinical onset of disease. The therapeutic efficacy of neutralizing endogenous IL-18 was...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Plater-Zyberk, Christine, Joosten, Leo A.B., Helsen, Monique M.A., Sattonnet-Roche, Pascale, Siegfried, Christiane, Alouani, Sami, van de Loo, Fons A.J., Graber, Pierre, Aloni, Shuki, Cirillo, Rocco, Lubberts, Erik, Dinarello, Charles A., van den Berg, Wim B., Chvatchko, Yolande
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209462/
https://ncbi.nlm.nih.gov/pubmed/11748266
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados