Role of protein kinase C-δ in the regulation of collagen gene expression in scleroderma fibroblasts
Working with cultured dermal fibroblasts derived from control individuals and patients with systemic sclerosis (SSc), we have examined the effects of protein kinase C-δ (PKC-δ) on type I collagen biosynthesis and steady-state levels of COL1A1 and COL3A1 mRNAs. Rottlerin, a specific inhibitor of PKC-...
Збережено в:
| Опубліковано в:: | J Clin Invest |
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| Автори: | , , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Clinical Investigation
2001
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11696585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12347 |
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