Role of protein kinase C-δ in the regulation of collagen gene expression in scleroderma fibroblasts

Working with cultured dermal fibroblasts derived from control individuals and patients with systemic sclerosis (SSc), we have examined the effects of protein kinase C-δ (PKC-δ) on type I collagen biosynthesis and steady-state levels of COL1A1 and COL3A1 mRNAs. Rottlerin, a specific inhibitor of PKC-...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Jimenez, Sergio A., Gaidarova, Svetlana, Saitta, Biagio, Sandorfi, Nora, Herrich, David J., Rosenbloom, Joan C., Kucich, Umberto, Abrams, William R., Rosenbloom, Joel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11696585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12347
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!