Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
Cardiac hypertrophy is a major cause of morbidity and mortality worldwide. The hypertrophic process is mediated, in part, by small G proteins of the Rho family. We hypothesized that statins, inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase, inhibit cardiac hypertrophy by blocking Rho isoprenyl...
Gespeichert in:
| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2001
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11714734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13350 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|