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Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-κB subunit p65
Both genotoxic and oncogenic stress activates the nuclear factor-kappa B (NF-κB) and p53 proteins; however, the p53 activity is antagonized by NF-κB signaling. Dmp1 is a Myb-like transcription factor that activates the Arf-p53 pathway. The Dmp1 promoter was activated by a classical NF-κB activator t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2094103/ https://ncbi.nlm.nih.gov/pubmed/17546045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210568 |
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