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Evidence for a role of NF-κB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor β fusion protein

Interleukin 3 (IL-3) and other hematopoietic cytokines transduce signals that stimulate DNA synthesis and cell survival. In certain chronic myelomonocytic leukemias, a TEL/platelet-derived growth factor receptor β (PDGFRβ) fusion protein is produced as a consequence of the t(5;12) translocation. It...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Besançon, Françoise, Atfi, Azeddine, Gespach, Christian, Cayre, Yvon E., Bourgeade, Marie-Françoise
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1998
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Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8081
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