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Complete heart block and sudden death in mice overexpressing calreticulin

The expression of calreticulin, a Ca(2+)-binding chaperone of the endoplasmic reticulum, is elevated in the embryonic heart, and because of impaired cardiac development, knockout of the Calreticulin gene is lethal during embryogenesis. The elevated expression is downregulated after birth. Here we ha...

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Detaylı Bibliyografya
Asıl Yazarlar: Nakamura, Kimitoshi, Robertson, Murray, Liu, Gang, Dickie, Peter, Nakamura, Kyoko, Guo, Ji Qing, Duff, Henry J., Opas, Michal, Kavanagh, Katherine, Michalak, Marek
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC209301/
https://ncbi.nlm.nih.gov/pubmed/11375414
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