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Complete heart block and sudden death in mice overexpressing calreticulin

The expression of calreticulin, a Ca(2+)-binding chaperone of the endoplasmic reticulum, is elevated in the embryonic heart, and because of impaired cardiac development, knockout of the Calreticulin gene is lethal during embryogenesis. The elevated expression is downregulated after birth. Here we ha...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nakamura, Kimitoshi, Robertson, Murray, Liu, Gang, Dickie, Peter, Nakamura, Kyoko, Guo, Ji Qing, Duff, Henry J., Opas, Michal, Kavanagh, Katherine, Michalak, Marek
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC209301/
https://ncbi.nlm.nih.gov/pubmed/11375414
Tagiau: Ychwanegu Tag
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