Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses

Fractalkine (FKN, CX3CL1) is a membrane-bound CX3C chemokine induced by primary proinflammatory signals in vascular endothelial cells (ECs). Here we examined the role of FKN in polarized Th1 or Th2 responses. Proinflammatory signals, including LPS, IL-1, TNF, and CD40 ligand, induced FKN, as did IFN...

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में प्रकाशित:	J Clin Invest
मुख्य लेखकों:	Fraticelli, Paolo, Sironi, Marina, Bianchi, Giancarlo, D’Ambrosio, Daniele, Albanesi, Cristina, Stoppacciaro, Antonella, Chieppa, Marcello, Allavena, Paola, Ruco, Luigi, Girolomoni, Giampiero, Sinigaglia, Francesco, Vecchi, Annunciata, Mantovani, Alberto
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Clinical Investigation 2001
विषय:	Article
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11342581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11517
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