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Cysteine Substitution Mutants Give Structural Insight and Identify ATP Binding and Activation Sites at P2X Receptors
P2X receptors for extracellular ATP are a distinct family of ligand-gated cation channels involved in physiological processes ranging from synaptic transmission to muscle contraction. Common ATP binding motifs are absent from P2X receptors, and the extent of the agonist binding site is unclear. We u...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2092412/ https://ncbi.nlm.nih.gov/pubmed/17428985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2310-06.2007 |
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