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Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation.

Streptomyces coelicolor produces four known antibiotics. To define genetic elements that regulate antibiotic synthesis, we screened for mutations that visibly blocked synthesis of the two pigmented antibiotics and found that the mutant strains which we recovered were of two classes--double mutants a...

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Vydáno v:J Bacteriol
Hlavní autoři: Adamidis, T, Riggle, P, Champness, W
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2345130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.6.2962-2969.1990
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