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Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation.

Streptomyces coelicolor produces four known antibiotics. To define genetic elements that regulate antibiotic synthesis, we screened for mutations that visibly blocked synthesis of the two pigmented antibiotics and found that the mutant strains which we recovered were of two classes--double mutants a...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Adamidis, T, Riggle, P, Champness, W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2345130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.6.2962-2969.1990
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