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Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation.

Streptomyces coelicolor produces four known antibiotics. To define genetic elements that regulate antibiotic synthesis, we screened for mutations that visibly blocked synthesis of the two pigmented antibiotics and found that the mutant strains which we recovered were of two classes--double mutants a...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Adamidis, T, Riggle, P, Champness, W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2345130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.6.2962-2969.1990
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