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The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor α

The Cbl protooncogene product has emerged as a negative regulator of receptor and nonreceptor tyrosine kinases. We recently demonstrated that oncogenic Cbl mutants upregulate the endogenous tyrosine kinase signaling machinery when expressed in the NIH 3T3 cells, and identified the platelet-derived g...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Miyake, Sachiko, Lupher, Mark L., Druker, Brian, Band, Hamid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC20906/
https://ncbi.nlm.nih.gov/pubmed/9653117
Tagiau: Ychwanegu Tag
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