Frameshift mutations in the bacteriophage Mu repressor gene can confer a trans-dominant virulent phenotype to the phage.

Virulent mutations in the bacteriophage Mu repressor gene were isolated and characterized. Recombination and DNA sequence analysis have revealed that virulence is due to unusual frameshift mutations which change several C-terminal amino acids. The vir mutations are in the same repressor region as th...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Geuskens, V, Vogel, J L, Grimaud, R, Desmet, L, Higgins, N P, Toussaint, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1833383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.20.6578-6585.1991
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