Frameshift mutations in the bacteriophage Mu repressor gene can confer a trans-dominant virulent phenotype to the phage.

Virulent mutations in the bacteriophage Mu repressor gene were isolated and characterized. Recombination and DNA sequence analysis have revealed that virulence is due to unusual frameshift mutations which change several C-terminal amino acids. The vir mutations are in the same repressor region as th...

Description complète

Détails bibliographiques

Publié dans:	J Bacteriol
Auteurs principaux:	Geuskens, V, Vogel, J L, Grimaud, R, Desmet, L, Higgins, N P, Toussaint, A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1833383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.20.6578-6585.1991
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!