Frameshift mutations in the bacteriophage Mu repressor gene can confer a trans-dominant virulent phenotype to the phage.

Virulent mutations in the bacteriophage Mu repressor gene were isolated and characterized. Recombination and DNA sequence analysis have revealed that virulence is due to unusual frameshift mutations which change several C-terminal amino acids. The vir mutations are in the same repressor region as th...

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Pubblicato in:	J Bacteriol
Autori principali:	Geuskens, V, Vogel, J L, Grimaud, R, Desmet, L, Higgins, N P, Toussaint, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1833383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.20.6578-6585.1991
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