An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene
Adenoviral (Ad)-mediated in vivo gene transfer and expression are limited in part by cellular immune responses to viral-encoded proteins and/or transgene immunogenicity. In an attempt to diminish the former responses, we have previously developed and described helper-dependent (HD) Ad vectors in whi...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653106/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.7866 |
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