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Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line

BACKGROUND: Agmatine is an endogenous polyamine formed by the decarboxylation of L-arginine. We investigated the protective effects of agmatine against hypoxia-induced apoptosis of immortalized rat retinal ganglion cells (RGC-5). RGC-5 cells were cultured in a closed hypoxic chamber (5% O(2)) with o...

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Detalhes bibliográficos
Main Authors: Hong, Samin, Lee, Jong Eun, Kim, Chan Yun, Seong, Gong Je
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2089075/
https://ncbi.nlm.nih.gov/pubmed/17908330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-81
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