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Calsequestrin determines the functional size and stability of cardiac intracellular calcium stores: Mechanism for hereditary arrhythmia

Calsequestrin is a high-capacity Ca-binding protein expressed inside the sarcoplasmic reticulum (SR), an intracellular Ca release and storage organelle in muscle. Mutations in the cardiac calsequestrin gene (CSQ2) have been linked to arrhythmias and sudden death. We have used Ca-imaging and patch-cl...

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Bibliografski detalji
Glavni autori: Terentyev, Dmitry, Viatchenko-Karpinski, Serge, Györke, Inna, Volpe, Pompeo, Williams, Simon C., Györke, Sandor
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC208831/
https://ncbi.nlm.nih.gov/pubmed/13130076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932318100
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