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The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene

Frequent allelic loss at human chromosome 11q23-q24 occurs in a wide variety of cancers, suggesting that this region may harbor a tumor suppressor gene. By constructing a physical map of the LOH11CR2 minimal region of loss on 11q23-q24 associated with lung and breast carcinomas, we were able to clon...

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Autores principales: Martin, Eric S., Cesari, Rossano, Pentimalli, Francesca, Yoder, Kristine, Fishel, Richard, Himelstein, Andrew L., Martin, S. Eric, Godwin, Andrew K., Negrini, Massimo, Croce, Carlo M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC208790/
https://ncbi.nlm.nih.gov/pubmed/14504409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1934602100
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