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Computational and Experimental Analyses of Mammalian Arylamine N-acetyltransferase Structure and Function
Arylamine N-acetyltransferases (NATs) play an important role in the metabolism of arylamine and hydrazine drugs and many arylamine pro-carcinogens. The two human N-acetyltransferases, NAT1 and NAT2, are widely distributed in human tissues and highly polymorphic. While many xenobiotic procarcinogens...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2085365/ https://ncbi.nlm.nih.gov/pubmed/17371801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.107.015040 |
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