α-Catenin is essential in intestinal adenoma formation

A loss-of-function mutation in the APC gene initiates colorectal carcinogenesis. Although the molecular mechanism of tumor initiation is complex, several modifier genes have been identified using mouse models, including the ApcMin mouse. Among the familial adenomatous polyposis mouse lines carrying...

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Detalhes bibliográficos
Main Authors: Shibata, Hiroyuki, Takano, Hiroshi, Ito, Masaki, Shioya, Hisashi, Hirota, Morihisa, Matsumoto, Hiroshi, Kakudo, Yuichi, Ishioka, Chikashi, Akiyama, Tetsu, Kanegae, Yumi, Saito, Izumu, Noda, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084320/
https://ncbi.nlm.nih.gov/pubmed/17989230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705730104
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