α-Catenin is essential in intestinal adenoma formation

A loss-of-function mutation in the APC gene initiates colorectal carcinogenesis. Although the molecular mechanism of tumor initiation is complex, several modifier genes have been identified using mouse models, including the ApcMin mouse. Among the familial adenomatous polyposis mouse lines carrying...

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Dades bibliogràfiques
Autors principals: Shibata, Hiroyuki, Takano, Hiroshi, Ito, Masaki, Shioya, Hisashi, Hirota, Morihisa, Matsumoto, Hiroshi, Kakudo, Yuichi, Ishioka, Chikashi, Akiyama, Tetsu, Kanegae, Yumi, Saito, Izumu, Noda, Tetsuo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084320/
https://ncbi.nlm.nih.gov/pubmed/17989230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705730104
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