β-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53

β-arrestins (β-arrs), two ubiquitous proteins involved in serpentine heptahelical receptor regulation and signaling, form constitutive homo- and heterooligomers stabilized by inositol 1,2,3,4,5,6-hexakisphosphate (IP6). Monomeric β-arrs are believed to interact with receptors after agonist activatio...

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Hlavní autoři: Boularan, Cédric, Scott, Mark G. H., Bourougaa, Karima, Bellal, Myriam, Esteve, Emmanuel, Thuret, Alain, Benmerah, Alexandre, Tramier, Marc, Coppey-Moisan, Maité, Labbé-Jullié, Catherine, Fåhraeus, Robin, Marullo, Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084296/
https://ncbi.nlm.nih.gov/pubmed/17984062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705550104
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