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Increasing Protein Conformational Stability by Optimizing β-turn Sequence

Protein conformational stability is an important concern in many fields. Here, we describe a strategy for significantly increasing conformational stability by optimizing β-turn sequence. Proline and glycine residues are statistically preferred at several β-turn positions, presumably because their un...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Trevino, Saul R., Schaefer, Stephanie, Scholtz, J. Martin, Pace, C. Nick
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084202/
https://ncbi.nlm.nih.gov/pubmed/17765922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.061
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