Promiscuous Mutations Activate the Non-Canonical NF-kB Pathway in Multiple Myeloma

Activation of NF-kB has been noted in many tumor types, however only rarely has this been linked to an underlying genetic mutation. An integrated analysis of high-density oligonucleotide array CGH and gene expression profiling data from 155 multiple myeloma samples identified a promiscuous array of...

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Autors principals: Keats, Jonathan J., Fonseca, Rafael, Chesi, Marta, Schop, Roelandt, Baker, Angela, Chng, Wee-Joo, Van Wier, Scott, Tiedemann, Rodger, Shi, Chang-Xin, Sebag, Michael, Braggio, Esteban, Henry, Travis, Zhu, Yuan-Xiao, Fogle, Homer, Price-Troska, Tammy, Ahmann, Gregory, Mancini, Catherine, Brents, Leslie A., Kumar, Shaji, Greipp, Philip, Dispenzieri, Angela, Bryant, Barb, Mulligan, George, Bruhn, Laurakay, Barrett, Michael, Valdez, Riccardo, Trent, Jeff, Stewart, A. Keith, Carpten, John, Bergsagel, P. Leif
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083698/
https://ncbi.nlm.nih.gov/pubmed/17692805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.07.003
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