Identification of copy-number abnormalities and inactivating mutations in two negative regulators of NF-kB signaling pathways in Waldenström’s Macroglobulinemia

Waldenström’s macroglobulinemia (WM) is a distinct clinico-biological entity defined as a B-cell neoplasm characterized by a lymphoplasmacytic infiltrate in the bone marrow (BM) and immunoglobulin M paraprotein production. Cytogenetic analyses were historically limited by the difficulty in obtaining...

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Auteurs principaux: Braggio, Esteban, Keats, Jonathan J, Leleu, Xavier, Van Wier, Scott, Jimenez-Zepeda, Victor H, Valdez, Riccardo, Schop, Roelandt FJ, Price-Troska, Tammy, Henderson, Kimberly, Sacco, Antonio, Azab, Feda, Greipp, Philip, Gertz, Morie, Hayman, Suzanne, Rajkumar, S Vincent, Carpten, John, Chesi, Marta, Barrett, Michael, Stewart, A Keith, Dogan, Ahmet, Bergsagel, P Leif, Ghobrial, Irene M, Fonseca, Rafael
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782932/
https://ncbi.nlm.nih.gov/pubmed/19351844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3701
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