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C/EBPα Induces PU.1 and Interacts with AP-1 and NF-κB to Regulate Myeloid Development

C/EBPα and PU.1 are key regulators of early myeloid development. Mice lacking C/EBPα or PU.1 have reduced granulocytes and monocytes. Consistent with a model in which induction of PU.1 by C/EBPα contributes to monocyte lineage specification, mice with reduced PU.1 have diminished monocytes but retai...

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Bibliografiske detaljer
Hovedforfatter: Friedman, Alan D.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083642/
https://ncbi.nlm.nih.gov/pubmed/17669672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2007.06.010
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