Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome

The experiments investigated the applicability of two established criteria for arrhythmogenicity in Scn5a+/Δ and Scn5a+/− murine hearts modelling the congenital long QT syndrome type 3 (LQT3) and the Brugada syndrome (BrS). Monophasic action potentials (APs) recorded during extrasystolic stimulation...

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Autors principals: Sabir, Ian N., Li, Lucia M., Jones, Victoria J., Goddard, Catharine A., Grace, Andrew A., Huang, Christopher L.-H.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2007
Matèries:
Cardiovascular System
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2082651/
https://ncbi.nlm.nih.gov/pubmed/17805561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-007-0326-z
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