Glycolipid and Ganglioside Metabolism Imbalances In Huntington’s Disease

We have explored genome-wide expression of genes related to glycobiology in exon 1 transgenic Huntington’s disease (HD) mice using a custom designed GLYCOv2 chip and Affymetrix microarray analyses. We validated, using quantitative real-time PCR, abnormal expression levels of genes encoding glycosylt...

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Main Authors: Desplats, Paula A., Denny, Christine A., Kass, Kristi E., Gilmartin, Tim, Head, Steven R., Sutcliffe, J. Gregor, Seyfried, Thomas N., Thomas, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2082128/
https://ncbi.nlm.nih.gov/pubmed/17600724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.05.003
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