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Novel pro- and anti-recombination activities of the Bloom’s syndrome helicase
Bloom’s syndrome (BS) is an autosomal recessive disorder characterized by a strong cancer predisposition. The defining feature of BS is extreme genome instability. The gene mutated in Bloom’s syndrome, BLM, encodes a DNA helicase (BLM) of the RecQ family. BLM plays a role in homologous recombination...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2081975/ https://ncbi.nlm.nih.gov/pubmed/18003860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1609007 |
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