Site-1 protease is essential for endochondral bone formation in mice

Site-1 protease (S1P) has an essential function in the conversion of latent, membrane-bound transcription factors to their free, active form. In mammals, abundant expression of S1P in chondrocytes suggests an involvement in chondrocyte function. To determine the requirement of S1P in cartilage and b...

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Autori principali: Patra, Debabrata, Xing, Xiaoyun, Davies, Sherri, Bryan, Jennifer, Franz, Carl, Hunziker, Ernst B., Sandell, Linda J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080931/
https://ncbi.nlm.nih.gov/pubmed/18025304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708092
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