Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis

B cell lymphoma 2 (Bcl-2) homology domain 3 (BH3)–only proteins of the Bcl-2 family are important functional adaptors that link cell death signals to the activation of Bax and/or Bak. The BH3-only protein Nbk/Bik induces cell death via an entirely Bax-dependent/Bak-independent mechanism. In contrast...

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Detalhes bibliográficos
Main Authors: Gillissen, Bernhard, Essmann, Frank, Hemmati, Philipp G., Richter, Antje, Richter, Anja, Öztop, Ilker, Chinnadurai, Govindaswamy, Dörken, Bernd, Daniel, Peter T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080900/
https://ncbi.nlm.nih.gov/pubmed/18025305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703040
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