A Comparative Immunogenicity Study of HIV-1 Virus-Like Particles Bearing Various Forms of Envelope Proteins, Particles Bearing no Envelope and soluble monomeric gp120

To assess the potential of native Envelope glycoprotein (Env) trimers as neutralizing antibody vaccines, we immunized guinea pigs with three types of VLPs and soluble gp120. Particles included “SOS-VLPs” (bearing disulfide-shackled functional trimers), “UNC-VLPs” (bearing uncleaved nonfunctional Env...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Crooks, Emma T., Moore, Penny L., Franti, Michael, Cayanan, Charmagne S., Zhu, Ping, Jiang, Pengfei, de Vries, Robbert P., Wiley, Cheryl, Zharkikh, Irina, Schülke, Norbert, Roux, Kenneth H., Montefiori, David C., Burton, Dennis R., Binley, James M.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080857/
https://ncbi.nlm.nih.gov/pubmed/17580087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.04.033
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires